Identification of the Genome-Wide Expression Patterns of Non-Coding RNAs Associated with Tanshinones Synthesis Pathway in Salvia miltiorrhiza

The red root of Salvia miltiorrhiza Bunge, a famous traditional Chinese medicine (TCM), was caused by tanshinone in epidermis cells. In order to study the biological function ncRNAs synthesis, expression patterns mRNA and were comprehensively analyzed (high content) white (low tissues derived from same plant. A total 731 differentially expressed genes (DEGs) mainly enriched primary metabolic pathways such as galactose nitrogen, some secondary phenylpropanoid terpenoids. 70 miRNAs, 48 lncRNAs, 26 circRNAs identified (DE) ones. enrichment pathway targets DE-lncRNA ribosome, carbon metabolism, plant hormone signal transduction, glycerophospholipid metabolism. 59 miRNAs combined with DE-circRNAs involved plant–pathogen interaction, endocytosis, biosynthesis, sesquiterpenoid triterpenoid biosynthesis pathways. Most synthesis had higher expression. Some predicted regulate several key enzyme pathway, SmDXS2, SmGGPPS1, SmKSL. Furthermore, most target related resistance pathogens. present exhibited tissue-specific ncRNAs, which would provide basis for further research into regulation mechanism process.